Thank you

Zephyr Valve treatment is indicated for patients with severe emphysema. Some patients with an advanced form of COPD (Chronic Obstructive Pulmonary Disease) may have emphysema. To be eligible for Zephyr Valve treatment, you must quit smoking.

Your doctor may be able to help you with a smoking cessation program.

Patient Stories

“Every day I find things I can do now I couldn’t do before.”– Michael McPheeter

View More Patient Stories

How the Zephyr Valve Works

The Zephyr Valve is the first minimally-invasive bronchoscopic treatment option in the United States for severe emphysema patients

See How It Works

Benefits & Risks

In a clinical study1, patients treated with the Zephyr Valve compared to patients on medication alone were able to:

Lungs Healthy Breath Zephyr

Breathe easier due to improved lung function

Walking Health Lungs Breathe

Increase their exercise – they could walk farther

Daily Activities Lung Health

Do more daily life activities, such as walking, bathing, and gardening

More Energy Lung Health Quality of Life

Enjoy a better quality of life with more energy

Confidence Quality of Life Lungs

Feel more confident leaving their home


Complications of the Zephyr Endobronchial Valve treatment can include but are not limited to pneumothorax, worsening of COPD symptoms, hemoptysis, pneumonia, dyspnea and, in rare cases, death.1

Prescriptive Information

There's a New Treatment Option Available

Emphysema cannot be cured, but the right treatment can help you breathe better, be more active, and improve your quality of life. There are a few treatment options for emphysema, and your doctor can help you determine which is best for you.

Spectrum of Treatment Options

Bronchodilator Inhaler COPD Emphysema

Oxygen Therapy, Corticosteroids, Bronchodilator

Pulmonary Rehab Zephyr Endobronchial Valve

Pulmonary Rehabilitation

Zephyr Lung Health Valve Pulmonx

Zephyr Endobronchial Valves

Lung Volume Reduction Surgery Invasive

Lung Volume Reduction Surgery

Lung Transplant Surgery Invasive

Lung Transplant


  • COPD medication – This may involve inhalers, oral steroids, antibiotics, or other prescription medications.
  • “Stop smoking” program – In order to benefit from minimally-invasive treatment options, you will be required to stop smoking to receive treatment.
  • Pulmonary rehabilitation – Your doctor may refer you to therapy to help you exercise your lungs and learn how to breathe more efficiently.
  • Oxygen therapy – Emphysema reduces the amount of oxygen that can reach your bloodstream. Your doctor may prescribe oxygen therapy when medication is not doing enough for you.


  • Zephyr Endobronchial Valve – The Zephyr Valve is a device for the treatment of emphysema. It is not another prescription medication or surgery that requires cutting or incisions. Instead, the Zephyr Valve treatment is a short medical procedure that is proven to help patients breathe easier, do more, and enjoy a better quality of life.
Learn More About The Zephyr Valve


  • Lung volume reduction surgery and bullectomy surgery – A surgeon will open your chest and cut out areas of damaged lung tissue, or large air spaces (bullae). It has been shown to improve patients’ breathing but has a risk of side effects and death.
  • Lung transplant – When the lungs are too damaged to benefit from surgery, certain patients may meet the criteria for lung transplantation surgery. If patients receive this treatment, they must take immune-suppressing medications for the rest of their lives. However, the transplant also carries high-risk complications such as organ rejection or death.